Oral cancer can sometimes be discovered without a biopsy



Oral cancer could be detected without the need for a biopsy in the not-too-distant future. Researchers at King George’s Medical University (KGMU) have taken a positive stride forward.

The Department of Health Research Organization’s multidisciplinary research unit (DHR-MRU), which is situated at KGMU, revealed promising results in a pilot study that discovered biomarkers in people’s blood and saliva that can diagnose oral cancer. Two studies looked into biomarkers in the blood to diagnose cancer and the role of Vitamin A and its compounds in cancer treatment and eradication.

Prof. Divya Mehrotra of the oral and maxillofacial surgery department explained: “The first investigation focuses on the biomarkers BCL2 and HSP 70. A total of 300 cancer and pre-cancerous people were included in the study. We arrived to the conclusion that these biomarkers can be utilised to diagnose cancer since the blood samples from the two groups were mixed. This will reduce the number of times a biopsy is required.” The second experiment, which included 250 patients with oral cancer, focused on Vitamin A.

“We investigated the impact of Vitamin A and related markers in these people and found that if the enzyme that breaks down Vitamin A isn’t functioning properly, these people are more likely to develop oral cancer. Antioxidant supplements are ineffectual in the treatment of these patients as well “she stated